Science News

[Utilisation of first-line antibiotics six years after a multifaceted intervention].

A new interesting article has been published in Rev Esp Quimioter. 2018 Dec;31(6):520-527. Epub 2018 Nov 5. English and titled:

[Utilisation of first-line antibiotics six years after a multifaceted intervention].

Authors of this article are:

Molero JM, Gómez M, Guerra G, Alcántara JD, Ortega J, García G, Pineda V, Munuera S, Cid M, Monedero MJ, Ribas JM, Cots JM, Moragas A, Bjerrum L, Llor C; Grupo de Trabajo HAPPY AUDIT .

A summary of the article is shown below:

OBJECTIVE: No study has evaluated the impact of a multifaceted intervention on the quality of the antibiotics prescribed more than 5 years later.METHODS: A total of 210 general practitioners (GP) from eight different regions of Spain were asked to participate in two registrations of respiratory tract infections (RTI) in 2008, before, and in 2009, just after a multifaceted intervention including prescriber feedback, clinical guidelines, training sessions focused on appropriate antibiotic prescribing, workshop on rapid tests and provision of these tests in the GP consultation. They were all again invited to participate in a similar registration in 2015. A new group of clinicians from the same areas who had never participated in antimicrobial stewardship courses were also invited to participate and acted as controls.RESULTS: The 121 GPs who continued the study (57.6%) and the 117 control GPs registered 22,407 RTIs. The antibiotic most commonly prescribed was amoxicillin and clavulanic acid, prescribed in 1,801 cases (8.1% of the total), followed by amoxicillin (1,372 prescriptions, 6.2%), being lower among GPs just after the intervention. The third leading antibiotic among GPs just after the intervention was penicillin V (127 cases, 3.3%) whereas macrolides ranked third in the other three groups of GPs.CONCLUSIONS: The use of first-line antibiotic for RTIs wanes over time after an intervention, but their utilisation is still significantly greater among intervened clinicians six years later compared to GPs who have never been exposed to any antimicrobial stewardship programmes.©The Author 2018. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(

Check out the article’s website on Pubmed for more information:

This article is a good source of information and a good way to become familiar with topics such as:



Categories: Science News