The mTOR Independent Function of Tsc1 and FNIPs.
Authors of this article are:
Sager RA, Woodford MR, Mollapour M.
A summary of the article is shown below:
New roles for Tsc1 and FNIP1/2 as regulators of the molecular chaperone Hsp90 were recently identified, demonstrating a broader cellular impact outside of AMPK-mTOR signaling. In studying the function of these proteins we must take a holistic view of the cell, instead of maintaining our focus on a single pathway.
Check out the article’s website on Pubmed for more information:
This article is a good source of information and a good way to become familiar with topics such as:
Birt-Hogg-Dubé syndrome;Hsp90;co-chaperone;mTOR;tuberous sclerosis complex
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