Science News

Maintaining the Health of the Renal Allograft: Laboratory and Histologic Monitoring After Kidney Transplantation.

A new interesting article has been published in Clin Lab Med. 2018 Dec;38(4):607-621. doi: 10.1016/j.cll.2018.07.003. Epub 2018 Oct 5. Review and titled:

Maintaining the Health of the Renal Allograft: Laboratory and Histologic Monitoring After Kidney Transplantation.

Authors of this article are:

Schinstock CA, Gandhi MJ.

A summary of the article is shown below:

Advances in posttransplant care, including new immunosuppressive medications have led to excellent short-term renal allograft survival. However, there is a small therapeutic window within which the patient and the clinician must balance the risk of rejection, with side effects such as infection, malignancy, and toxicity. Laboratory testing plays a key role in this ongoing monitoring, which includes relatively simple tests, such as serum creatinine, to complex tests, such as solid-phase assays, used to monitor for donor-specific antibody and surveillance allograft biopsies. This article reviews the role of the laboratory tests and surveillance biopsies in posttransplant monitoring.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as:

De novo donor-specific antibodies;Posttransplant GFR;Posttransplant monitoring;Posttransplant proteinuria;Surveillance biopsy

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