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Linking sleep disturbance to idiopathic male infertility.

A new interesting article has been published in Sleep Med Rev. 2018 Dec;42:149-159. doi: 10.1016/j.smrv.2018.07.006. Epub 2018 Aug 3. Review and titled:

Linking sleep disturbance to idiopathic male infertility.

Authors of this article are:

Palnitkar G, Phillips CL, Hoyos CM, Marren AJ, Bowman MC, Yee BJ.

A summary of the article is shown below:

Recently published data suggests that male fertility has declined over the past four decades. The reasons for the decline are unclear with up to 50% of cases of male infertility remaining unexplained (idiopathic male infertility). Whilst environmental factors and rising rates of obesity have been implicated, there is now growing evidence that sleep disturbance may be an independent causative factor. Indeed, the prevalence of sleep disturbance appears to be increasing in parallel with deterioration in population sperm quality, a commonly used surrogate marker of male fertility. Although there is some understanding of the relationship between sleep, gonadal hormone secretion and sexual function, it remains to be seen whether sleep disturbance is implicated in idiopathic male infertility. This review will detail the current evidence supporting a link between sleep disturbance and male infertility. Potential mechanistic pathways will be proposed and evidence supporting these pathways will be discussed. Further research is needed in clarifying links between sleep disturbance and idiopathic male infertility. At present the only available treatment option for men with idiopathic infertility is assisted reproductive technology. Demonstration of a causative link between sleep disturbance and idiopathic male infertility may in the future lead to additional treatment options in selected cases.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as:

DNA fragmentation;Infertility;Male infertility;Obstructive sleep apnoea;Reproductive hormones;Sleep;Sleep disturbance

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