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Recognizing Hereditary Renal Cancers Through the Microscope: A Pathology Update.

A new interesting article has been published in Surg Pathol Clin. 2018 Dec;11(4):725-737. doi: 10.1016/j.path.2018.07.010. Epub 2018 Oct 17. Review and titled:

Recognizing Hereditary Renal Cancers Through the Microscope: A Pathology Update.

Authors of this article are:

Peng YC, Chen YB.

A summary of the article is shown below:

A heightened understanding of hereditary renal cancer syndromes and their molecular basis has led to an increased awareness and recognition of these renal neoplasms by pathologists. Because a diagnosis of hereditary renal cell carcinoma has a profound impact on the patient and family members, when and how to raise such a suspicion via pathologic assessment has become an important yet very challenging task. This review discusses key clinicopathologic, immunohistochemical, and genetic characteristics of hereditary renal cancer syndromes, and important differential diagnostic challenges, emphasizing recent pathologic and molecular advances.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as:

Birt-Hogg-Dubé;Familial;Hereditary leiomyomatosis renal cell carcinoma;Hereditary papillary;Kidney cancer;Succinate dehydrogenase;Tuberous sclerosis;von Hippel-Lindau

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