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DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H11)₂]-Synthesis, Properties, and Applications.

A new interesting article has been published in Int J Mol Sci. 2018 Nov 7;19(11). pii: E3501. doi: 10.3390/ijms19113501. Review and titled:

DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H11)₂]-Synthesis, Properties, and Applications.

Authors of this article are:

Olejniczak AB, Nawrot B, Leśnikowski ZJ.

A summary of the article is shown below:

Together with tremendous progress in biotechnology, nucleic acids, while retaining their status as “molecules of life”, are becoming “molecular wires”, materials for the construction of molecular structures at the junction between the biological and abiotic worlds. Herein, we present an overview of the approaches for incorporating metal centers into nucleic acids based on metal⁻boron cluster complexes (metallacarboranes) as the metal carriers. The methods are modular and versatile, allowing practical access to innovative metal-containing DNA for various applications, such as nucleic acid therapeutics, electrochemical biosensors, infrared-sensitive probes, and building blocks for nanoconstruction.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as:

DNA;boron clusters;metallacarboranes;oligonucleotide probes;therapeutic nucleic acids

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