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Dengue fever: a worldwide threat An overview of the infection process, environmental factors for global outbreak, diagnostic platforms, and vaccine…

A new interesting article has been published in Curr Top Med Chem. 2018 Nov 5. doi: 10.2174/1568026618666181105130000. [Epub ahead of print] and titled:

Dengue fever: a worldwide threat An overview of the infection process, environmental factors for global outbreak, diagnostic platforms, and vaccine…

Authors of this article are:

Hosseini S, Oliva-Ramírez J, Vázquez-Villegas P, García AR, Muñoz-Soto RB, Aghamohammadi N, Martinez-Chapa SO.

A summary of the article is shown below:

Current review article focuses on Dengue, which is one of the most fatal infectious illnesses and is considered to be a worldwide threat. The paper covers essential topics including an overview on neglected tropical diseases with specific emphasis on Dengue fever, mosquito’s cycle of life and mechanism of infection, adaptive response, and different stages in Dengue immunopathogenesis. The current work is also dedicated to the thorough study of Dengue outbreak across the globe with narrowed study to tropical and subtropical regions. Moreover, this review article demonstrates the correlation between the climate factors and Dengue incidence. Furthermore, we present an overview on the detection strategies of Dengue including the latest developments in commercial and non-commercial platforms. Several attempts in developing effective vaccine to protect individuals from Dengue infection and the stage of clinical trails are gathered in the present work as well. Future directions including bio-control are also discussed in this review article. In an overall view, effective management of Dengue is a multidisciplinary task that requires international involvement from different backgrounds and expertise to address this global concern. This review article briefly portrays some of these connecting areas across the disciplines while many other perspectives remain uncovered.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as:

Bio-control of Dengue. ;Dengue fever;Dengue immunopathogenesis;Dengue outbreak;Detection platforms for Dengue;Effect of climate factors on Dengue

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