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Severe pelvic organ prolapse. Is there a long-term cure?

A new interesting article has been published in Int Urogynecol J. 2018 Sep 25. doi: 10.1007/s00192-018-3775-3. and titled:

Severe pelvic organ prolapse. Is there a long-term cure?

Authors of this article are:
Athanasiou S Zacharakis D Protopapas A Pitsouni E Loutradis D Grigoriadis T.

A summary of the article is shown below:
INTRODUCTION AND HYPOTHESIS: Vaginally assisted laparoscopic sacrocolpopexy (VALS) is a combined vaginal and laparoscopic surgical approach that has been described for the treatment of women with a uterus who suffer from severe multicompartmental pelvic organ prolapse (POP). The aim of this study is to evaluate the long-term anatomical and functional outcomes and report the long-term mesh-related complications.METHODS: This was a single-center prospective study of women with advanced POP who underwent VALS with at least 3 years of follow-up. The primary outcome was “composite surgical success” defined as: (1) no descent of the vaginal apex (point C) more than one-third into the vaginal canal and no anterior or posterior vaginal wall beyond the hymen (Ba and Bp < 0) (anatomical success), (2) no vaginal bulge symptoms and (3) no re-treatment for prolapse recurrence.RESULTS: The median follow-up was 7 years (range 3-10 years) with a composite surgical success rate of 95.7% (90/94). Failures (4.3%) included one (1.1%) case of anatomical recurrence (Bp: +1), one woman (1.1%) reporting vaginal bulge symptoms and two women (2.1%) who underwent a posterior colporrhaphy 6 and 12 months after primary surgery (reoperation rate: 2.1%). Two of 94 patients (2.1%) had been treated for mesh extrusion of the vaginal cuff prior to the follow-up visit.CONCLUSIONS: The combined VALS technique can be considered a safe and effective procedure for the treatment of severe POP allowing a long-term anatomical restoration of all compartments with excellent functional outcomes.
Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: Long-term outcome;Mesh;Pelvic organ prolapse;Prolapse recurrence;Sacrocolpopexy.

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