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Primary prevention of dementia: from modifiable risk factors to a public brain health agenda?

A new interesting article has been published in Soc Psychiatry Psychiatr Epidemiol. 2018 Sep 25. doi: 10.1007/s00127-018-1598-7. Review and titled:

Primary prevention of dementia: from modifiable risk factors to a public brain health agenda?

Authors of this article are:
Hussenoeder FS Riedel-Heller SG.

A summary of the article is shown below:
INTRODUCTION: With large numbers of people affected, no treatment in sight and continuing demographic change, the prevention of dementia is becoming a central public health issue.METHODS: We conducted a systematic meta-review including systematic reviews and meta-analyses of longitudinal observational studies on modifiable risk and protective factors for dementia published over the last 5 years.RESULTS: Compelling evidence on a number of modifiable risk factors, mostly lifestyle factors, is available from longitudinal observational studies to inform primary preventive efforts.DISCUSSION: Evidence stemming from preventive RCTs is limited. However, multi-domain interventions addressing a variety of risk factors at once seem promising with regard to high-risk individuals (selective preventive approach). However, we argue that it is time to move forward and discuss a public brain health agenda as a universal preventive approach. Based on a risk reduction strategy, the public brain health agenda suggests the following ten key actions: (1) increase physical activity, (2) foster social integration, (3) improve education and foster lifelong learning, (4) provide mentally stimulating workplaces, (5) foster a cognitively active lifestyle, (6) propose a healthy Mediterranean-like diet, (7) reduce alcohol consumption, (8) stop smoking, (9) prevent, diagnose and treat chronic conditions, and (10) reduce anticholinergic medication in the elderly.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: Brain health agenda;Dementia;Prevention;Risk factors;Systematic review.

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