Science News

Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder.

A new interesting article has been published in J Obstet Gynaecol Res. 2018 Sep 25. doi: 10.1111/jog.13825. Case Reports and titled:

Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder.

Authors of this article are:
Sotodate G Matsumoto A Konishi Y Toya Y Endo M Oyama K.

A summary of the article is shown below:
Vitamin K deficiency in pregnant women causes intracranial hemorrhage (ICH) in fetuses. Fetal ICH frequently causes life-threatening and persistent neurological damage. However, indicators for preventing fetal ICH are not established. Two pregnant women developed long-term eating disorders caused by psychosis. They were administered intravenous fluid and vitamin supplementation, excluding vitamin K. The intracranial low-hypoechoic area on fetal ultrasound was suggestive of fetal ICH due to vitamin K deficiency. Their neonates showed severe developmental delay. Laboratory analysis revealed a normal prothrombin time, but elevated protein induced by vitamin K absence II. Pregnant women who have eating disorders more than 3 weeks could develop fetal ICH due to maternal subclinical vitamin K deficiency. Illness duration and protein induced by vitamin K absence II of pregnant woman may be indicators for vitamin K administration to prevent fetal intracranial hemorrhage.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: PIVKA-II;eating disorder;fetus;intracranial hemorrhage;vitamin K deficiency.

Categories: Science News