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Post Syrian war impact on susceptibility rates and trends in molecular characterization of Enterobacteriaceae.

A new interesting article has been published in Future Microbiol. 2018 Sep;13:1419-1430. doi: 10.2217/fmb-2018-0109. Epub 2018 Sep 26. and titled:

Post Syrian war impact on susceptibility rates and trends in molecular characterization of Enterobacteriaceae.

Authors of this article are:
Hajj A Adaimé A Hayajneh W Abdallah A Itani T Hakimé N Mallah M Alsamarneh R Badal R Sarkis DK.

A summary of the article is shown below:
OBJECTIVE: Describe susceptibility and molecular profiles among Enterobacteriaceae pathogens and to explore if war, among other factors, can affect antimicrobial resistance.METHODS: Clinical isolates from the Study for Monitoring Antimicrobial Resistance Trends associated with urinary tract and intra-abdominal infections between 2011 and 2015 were identified in Lebanon and Jordan. Susceptibility testing and molecular characterization were performed as per standard methods.RESULTS: A total of 1486 Enterobacteriaceae pathogens (including unusual pathogens) were identified. Incidence rates of  extended spectrum β-lactamases were high with an overall higher prevalence of resistance in Jordan compared with Lebanon. CTX-M-15 was the most prevalent extended spectrum β-lactamases produced and OXA-48 the most reported carbapenemases subtype.CONCLUSION: Changes in healthcare system due to war could impact regional resistance patterns and which requires a continuous surveillance program and containment plan.

Check out the article’s website on Pubmed for more information:



This article is a good source of information and a good way to become familiar with topics such as: Enterobacteriaceae;Jordan;Lebanon;SMART;Syrian war;intra-abdominal infection;molecular characterization;resistance;urinary-tract infection;β-lactamases.

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