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Palladium-Catalyzed C-S Bond Cleavage with Allenoates: Synthesis of Tetrasubstituted 2-Alkenylfuran Derivatives.

A new interesting article has been published in Org Lett. 2018 Oct 5;20(19):6007-6011. doi: 10.1021/acs.orglett.8b02253. Epub 2018 Sep 26. and titled:

Palladium-Catalyzed C-S Bond Cleavage with Allenoates: Synthesis of Tetrasubstituted 2-Alkenylfuran Derivatives.

Authors of this article are:
Wang Q Liu Z Lou J Yu Z.

A summary of the article is shown below:
Palladium-catalyzed C-S cleavage of tetrasubstituted internal alkene α-oxo ketene dithioacetals was realized with allenoates as the coupling partners, efficiently affording tetrasubstituted 2-alkenylfuran derivatives with excellent regioselectivity under mild conditions. Allenoates acted as C1 synthons in the desulfurative [4 + 1] annulation.

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