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An NNN-Pincer-Cobalt Complex Catalyzed Highly Markovnikov-Selective Alkyne Hydrosilylation.

A new interesting article has been published in Org Lett. 2018 Oct 5;20(19):6265-6269. doi: 10.1021/acs.orglett.8b02746. Epub 2018 Sep 26. and titled:

An NNN-Pincer-Cobalt Complex Catalyzed Highly Markovnikov-Selective Alkyne Hydrosilylation.

Authors of this article are:
Zhang S Ibrahim JJ Yang Y.

A summary of the article is shown below:
A new NNN pincer (amine-pyridine-imine, API) cobalt complex, which is bench-stable and is applicable for the highly efficient and regioselective hydrosilylation of terminal alkynes, is developed. A broad set of α-vinylsilanes was successfully synthesized in good to high yields with up to 98/2 Markovnikov regioselectivity. This protocol can be readily scaled up for gram-scale synthesis and demonstrates the most efficient cobalt-catalyzed hydrosilylation of alkynes with turnover frequencies as high as 126 720 h-1 to date.

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