Pharmaceutics Calculations Practice Set #12 with Answers

Pharmaceutics Calculations Practice Set #12 with Answers
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Question 1
Calculate the NaCl equivalent of 1% solution of pilocarpine nitrate (MW = 271; i = 1.8).
A. 0.18
B. 0.22
C. 0.27
D. 0.30

Question 2
How many grams of potassium nitrate could be used to make the following prescription isotonic?
Rx) Sol. Silver Nitrate 60 mL
1:500 w/v
Make isoton. Sol.
Sig. For eye use
S. N. E = 0.33
P. N. E = 0.58
A. 0.5
B. 0.86
C. 0.54
D. 0.6

Question 3
How many grams of sodium chloride should be used in compounding the following prescription?
Pilocarpine Nitrate 0.3 g (E = 0.23)
Sodium Chloride q.s.
Purified Water ad 30 mL
Make isotonic solution
Sig. For the eye
A. 0.4
B. 0.15
C. 0.2
D. 0.35

Question 4
Determine the volume of purified water and 0.9% w/v NaCl solution needed to prepare 20 mL of a 1% w/v solution of hydromorphone HCl (E=0.22)
A. 4.9 & 15.1
B. 0 & 20
C. 10 & 10
D. 15 & 5

Question 5
Using the E values, calculate the number of mL of water required to make an isotonic solution from 0.3 g of each of the following:
A. 11
B. 8
C. 5
D. 7.6
B 1. chlorobutanol [E = 0.24]
D 2. ephedrine sulfate [E=0.23]
A 3. silver nitrate [E=0.33]
C 4. zinc sulfate [E=0.15]

Question 6
Calculate the E values for each of the following, given that the number of mL of water shown will produce an isotonic solution from 0.3 g of drug.
A. 0.08
B. 0.22
C. 0.16
D. 0.2
C 1. Ethylmorphine HCl, 5.3 mL water
D 2. Holocaine HCl, 6.7 mL water
B 3. Procainamide HCl, 7.3 mL water
A 4. Viomycin sulfate, 2.7 mL water